Transmyocardial and percutaneous myocardial laser revascularization.

نویسندگان

  • Duncan C McNab
  • Peter M Schofield
چکیده

tables or figures and should relate solely to an article published in Circulation within the preceding 12 weeks. Authors of letters selected for publication will receive prepublication proofs, and authors of the article cited in the letter will be invited to reply. Replies must be signed by all authors listed in the original publication. Please submit three typewritten, double-spaced copies of the letter to Herbert L. Fred, MD, the Circulation Editorial Office. Letters will not be returned.

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Myocardial laser revascularization for the treatment of end-stage coronary artery disease.

Myocardial laser revascularization is a novel therapeutic technique aimed at delivering oxygenated blood via a series of channels to the ischemic regions of the heart. These channels may be created surgically or via a less invasive percutaneous approach. In patients with end-stage coronary artery disease, both transmyocardial laser revascularization (TMR) and percutaneous myocardial laser revas...

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Myocardial laser revascularization.

Some patients with severe angina have coronary artery disease which is unsuitable for conventional forms of revascularization — coronary angioplasty/ stenting or coronary artery bypass surgery. These patients have usually undergone previous revascularization procedures and have disease which is diffuse and affects the distal part of the coronary circulation. Transmyocardial laser revascularizat...

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Mechanism of TMR; the debate continues.

Clinical experience with transmyocardial laser revascularization has increased significantly over the last few years. Since several transmyocardial laser revascularization studies reported an apparent effect on the relief of angina and the FDA approved reimbursement of transmyocardial laser revascularization procedures in the USA, thousands of patients have been treated worldwide with different...

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Use of magnetic resonance imaging to assess myocardial perfusion after transmyocardial laser revascularization.

BACKGROUND Transmyocardial laser revascularization (TMLR) is an alternative treatment modality for patients with refractory angina who are not candidates for conventional surgical or percutaneous revascularization. Clinical studies of TMLR have not shown one-to-one correlation between increased myocardial perfusion and improved clinical status. METHODS Three patients (51, 53, and 70 years old...

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Improvement of myocardial contractility in a porcine model of chronic ischemia using a combined transmyocardial revascularization and gene therapy approach.

OBJECTIVES The purpose of this study was to investigate whether a novel fibroblast growth factor-2 gene formulation, providing a localized and sustained availability of the adenoviral vector from a collagen-based matrix, in combination with CO 2 transmyocardial laser revascularization would lead to an enhanced angiogenic response and improved myocardial function. METHODS Fibroblast growth fac...

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Improved myocardial perfusion after transmyocardial laser revascularization in a patient with microvascular coronary artery disease

We report the case of a 59-year-old woman who presented with symptoms of angina that was refractory to medical management. Although her cardiac catheterization revealed microvascular coronary artery disease, her symptoms were refractory to optimal medical management that included ranolazine. After undergoing transmyocardial revascularization, her myocardial ischemia completely resolved and her ...

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عنوان ژورنال:
  • Circulation

دوره 105 19  شماره 

صفحات  -

تاریخ انتشار 2002